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Rabbit Anti-Swine IL-1RN Polyclonal Antibody

Cat. No.VD10H79

Product TypeAnimal-targeted Antibodies

Size

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Product Overview

O17H79 polyclonal antibody is specific for Swine Interleukin-1 receptor antagonist protein (IL-1RN), also known as IL-1RA. It was purified by affinity chromatography on Protein A from tissue culture supernatant. It can be applied for Western Blot (WB).

Specifications

Application WB

Clonality Polyclonal Antibody

Classification Primary Antibody

Clone O17H79

Host Rabbit

Target Species Swine

Species Reactivity Swine

Specificity Swine IL1RN

Immunogen Recombinant IL1RA expressed in E. coli.

Purification Protein A Purified

Purity ≥ 90% (SDS-PAGE)

Concentration 0.5 mg/mL

Conjugation Unconjugated

Preservative and Stabilizer 0.02% Sodium azide (NaN₃), 50% Glycerol

Buffer Phosphate buffered saline

Physical State Liquid

Target Information

Interleukin-1 receptor antagonist protein (IL-1RN), also known as IL-1RA is a member of the interleukin 1 cytokine family. IL-1RN is secreted by various types of cells including immune cells, epithelial cells, and adipocytes, and is a natural inhibitor of the pro-inflammatory effect of IL1β. Swine IL1RN is a single non-glycosylated polypeptide chain that is able to block the inflammatory responses induced by IL1 both in vitro and in vivo. IL-1RN is an important natural anti-inflammatory protein in arthritis, colitis, and granulomatous pulmonary disease.

Target Swine IL-1RN

Target Synonym IL-1ra; IL1F3; IL1RA; MVCD4; IL1 inhibitor; IL1RN (IL1F3); IRAP; ICIL-1RA; IL-1ra3

Gene ID 397499

UniProt ID Q29056

Shipping and Storage

This product is shipped with gel ice packs. It is recommended to store at -20 °C on receipt (up to 12 months).

Documents

Datasheet

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

Tomczyk, Monika, et al. "Anandamide influences interleukin-1β synthesis and IL-1 system gene expressions in the ovine hypothalamus during Endo-toxin-induced inflammation." Animals 11.2 (2021): 484.