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Mouse Anti-Canine Lactate Dehydrogenase A (LDHA) Monoclonal Antibody

Cat. No.VD11N56

Product TypeAnimal-targeted Antibodies

Size 100 μL

Product Overview

BioVenic mouse monoclonal antibody is specific for canine lactate dehydrogenase A. It can be applied to WB; IHC and IP assays of canine lactate dehydrogenase A.

Specifications

Application WB; IHC; IP
Clonality Monoclonal
Classification Primary Antibody
Clone S13N8
Host Mouse
Target Species Canine
Species Reactivity Canine
Specificity Canine Lactate Dehydrogenase A
Isotype IgG1
Immunogen Recombinant protein of lactate dehydrogenase A
Concentration 1 mg/mL
Conjugation Unconjugated
Preservative and Stabilizer 0.02% Sodium Azide
Buffer Phosphate Buffered Saline, 1% BSA, 50% Glycerol
Physical State Liquid

Target Information

Canine lactate dehydrogenase A (LDHA) is a key enzyme involved in the conversion of pyruvate to lactate during anaerobic glycolysis, playing a crucial role in energy metabolism, especially under hypoxic conditions. This enzyme facilitates the Warburg effect, where cancer cells preferentially utilize glycolysis for energy production, even in the presence of oxygen. Elevated levels of LDHA have been linked to tumor growth, maintenance, and invasion, making it a promising target for cancer diagnosis and therapy. In dogs, understanding LDHA's function can provide insights into metabolic disorders and the development of therapeutic strategies for conditions such as cancer, where LDHA inhibition may restrict tumor energy supply and reduce malignancy.

Target Canine Lactate Dehydrogenase A
Target Synonym LDHA
Gene ID 476882
UniProt ID A0A8C0PCN9

Shipping and Storage

This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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