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Mouse Anti-Canine Lysine Specific Histone Demethylase 1A (LSD1) Monoclonal Antibody
Product Overview
BioVenic mouse monoclonal antibody is specific for canine lysine specific histone demethylase 1A. It is purified by affinity chromatography. It can be applied to WB, IHC and IF assays of canine lysine specific histone demethylase 1A.
Specifications
Target Information
Canine Lysine Specific Histone Demethylase 1A (LSD1/KDM1A) is a FAD-dependent enzyme that plays a crucial role in the regulation of gene expression through its demethylase activity. It removes methyl groups from mono- and dimethylated lysine 4 on histone H3 (H3K4me1/2) and occasionally lysine 9 (H3K9me1/2), which are modifications associated with active gene transcription. LSD1's action counterbalances the methylation marks added by histone methyltransferases, thus playing a critical role in the dynamic regulation of chromatin structure. It can also demethylate non-histone proteins, including the tumor suppressor p53.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.