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Mouse Anti-Canine PSMC3 Monoclonal Antibody

Product Overview

BioVenic mouse monoclonal antibody is specific for canine PSMC3. It can be applied to WB, ICC/IF, IHC and FACS assays of canine PSMC3.

Specifications

Application WB, ICC/IF, IHC, FACS

Clonality Monoclonal

Classification Primary Antibody

Clone S13N28

Host Mouse

Target Species Canine

Species Reactivity Canine

Specificity Canine PSMC3

Isotype IgG1

Immunogen Recombinant protein of PSMC3

Concentration 0.58 mg/mL

Conjugation Unconjugated

Preservative and Stabilizer 0.02% Sodium Azide

Buffer Phosphate Buffered Saline, 1% BSA, 50% Glycerol

Physical State Liquid

Target Information

Canine PSMC3, a component of the 26S proteasome, plays a pivotal role in the regulation of protein homeostasis through its involvement in the ubiquitin-proteasome system. This protein is essential for the efficient RNAi response, as its depletion can abolish siRNA-mediated cleavage of target mRNAs, highlighting its importance in gene silencing mechanisms. PSMC3 is also required for miR-21-mediated mRNA cleavage, indicating its role in microRNA function.

Target Canine PSMC3

Gene ID 475980

UniProt ID A0A8I3PF55

Shipping and Storage

This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.

Documents

Datasheet

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.