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Mouse Anti-Porcine Argininosuccinate Lyase (ASL) Monoclonal Antibody
Product Overview
BioVenic mouse monoclonal antibody is specific for argininosuccinate lyase. It is affinity purified by protein A. It can be applied to WB and ELISA assays of argininosuccinate lyase.
Specifications
Target Information
Porcine argininosuccinate lyase (pASL) is an enzyme that plays a critical role in the urea cycle, a metabolic pathway responsible for the detoxification of ammonia in mammals. pASL catalyzes the conversion of argininosuccinate to arginine and fumarate, a reaction that is essential for the production of urea from ammonia and is a key step in maintaining nitrogen balance within the body. This enzyme is predominantly found in the liver, where it functions to mitigate the toxic effects of ammonia by incorporating it into the urea molecule, which can then be safely excreted. pASL is also present in other tissues, including the kidneys, where it may contribute to additional metabolic processes.
Shipping and Storage
This product is shipped with ice gel packs. Store at -20°C on receipt.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Zheng, Liang, et al. "Reversed argininosuccinate lyase activity in fumarate hydratase-deficient cancer cells." Cancer & metabolism 1 (2013): 1-11.