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Mouse Anti-Porcine Protein Phosphatase 1 Catalytic Subunit Alpha Isoform (PPP1CA) Monoclonal Antibody

Cat. No.VD8N258

Product TypeAnimal-targeted Antibodies

Size

Product Overview

BioVenic mouse monoclonal antibody is specific for protein phosphatase 1 catalytic subunit alpha isoform. It is affinity purified by protein A. It can be applied to WB and ELISA assays of protein phosphatase 1 catalytic subunit alpha isoform.

Specifications

Application WB; ELISA
Clonality Monoclonal
Classification Primary Antibody
Clone G6N2
Host Mouse
Target Species Porcine
Species Reactivity Porcine
Specificity Protein Phosphatase 1 Catalytic Subunit Alpha Isoform
Isotype IgG1
Immunogen Recombinant protein of protein phosphatase 1 catalytic subunit alpha isoform
Purification Protein A Purified
Concentration 1000 μg/mL
Conjugation Unconjugated
Preservative and Stabilizer 0.02% Sodium Azide
Buffer Phosphate Buffered Saline with 50% Glycerol, pH 7.3
Physical State Liquid

Target Information

Porcine protein phosphatase 1 catalytic subunit alpha isoform (PP1α) is a key enzyme in the porcine cellular machinery, playing a central role in the regulation of protein phosphorylation. PP1α is a component of Protein Phosphatase 1 (PP1), a highly conserved serine/threonine phosphatase that counterbalances the actions of kinases by dephosphorylating target proteins, thus modulating their activity. This isoform, PP1α, is particularly important in various cellular processes, including glycogen metabolism, muscle contraction, and signal transduction. It is highly expressed in skeletal muscle and the brain, where it contributes to the regulation of glycogen synthesis and neuronal function, respectively.

Target Protein Phosphatase 1 Catalytic Subunit Alpha Isoform
Target Synonym PP 1A; PPP1A
Gene ID 733611
UniProt ID P60588

Shipping and Storage

This product is shipped with ice gel packs. Store at -20°C (up to 12 months) on receipt.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

  1. Zhang, A. J., et al. "Expression of the catalytic subunit of phosphorylase phosphatase (protein phosphatase-1) in Escherichia coli." Journal of Biological Chemistry 267.3 (1992): 1484-1490.
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