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Mouse Anti-Porcine Developmentally Regulated GTP Binding Protein 2 (DRG2) Monoclonal Antibody

Cat. No.VD8N376

Product TypeAnimal-targeted Antibodies

Size

Product Overview

BioVenic mouse monoclonal antibody is specific for developmentally regulated GTP binding protein 2. It is affinity purified by protein A. It can be applied to WB, IF and ELISA assays of developmentally regulated GTP binding protein 2.

Specifications

Application WB; IF; ELISA
Clonality Monoclonal
Classification Primary Antibody
Clone G8N29
Host Mouse
Target Species Porcine
Species Reactivity Porcine
Specificity Developmentally Regulated GTP Binding Protein 2
Isotype IgG2
Immunogen Recombinant protein of developmentally regulated GTP binding protein 2
Purification Protein A Purified
Concentration 2400 μg/mL
Conjugation Unconjugated
Preservative and Stabilizer 0.02% Sodium Azide
Buffer Phosphate Buffered Saline with 50% Glycerol, pH 7.3
Physical State Liquid

Target Information

Porcine developmentally regulated GTP binding protein 2 (pDRG2), also known as Dynamin 2 (DNM2), is a member of the dynamin family of large GTPases that are integral to cellular processes involving membrane dynamics. pDRG2 plays a crucial role in the regulation of endocytosis, the process by which cells internalize molecules from their external environment, and is particularly important during development and in maintaining cellular homeostasis. This protein is expressed in various tissues and is involved in the fission of vesicles from the plasma membrane, a process that requires the hydrolysis of GTP to GDP. pDRG2 is also implicated in the regulation of actin dynamics and microtubule interactions, which are essential for cellular motility and the establishment of cell polarity.

Target Developmentally Regulated GTP Binding Protein 2
Target Synonym DRG 2; DRG2
Gene ID 445516
UniProt ID A0A287BSQ1

Shipping and Storage

This product is shipped with ice gel packs. Store at -20°C (up to 12 months) on receipt.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

  1. Ko, Myoung Seok, et al. "Developmentally regulated GTP-binding protein 2 ameliorates EAE by suppressing the development of TH17 cells." Clinical Immunology 150.2 (2014): 225-235.
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