Mouse Anti-Porcine Hydroxyacyl-Coenzyme A Dehydrogenase Subunit Beta (HADHB) Monoclonal Antibody

Porcine hydroxyacyl-coenzyme A dehydrogenase subunit beta (HADHB) is a component of the mitochondrial trifunctional protein (MTP), which is crucial for the beta-oxidation of long-chain fatty acids. This enzyme complex is composed of four subunits, with HADHB encoding the beta subunit that harbors the 3-ketoacyl-CoA thiolase activity, an essential step in the breakdown of fatty acids within the mitochondria. In pigs, HADHB plays a vital role in energy metabolism, particularly during periods of high energy demand, such as growth, reproduction, and lactation. Its function is not only limited to energy production but also extends to the maintenance of metabolic health, as deficiencies in HADHB can lead to the accumulation of toxic metabolites, which can be detrimental to cellular function.