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Mouse Anti-Porcine Myosin Regulatory Light Chain 2 (MLC-2V) Monoclonal Antibody
Product Overview
BioVenic mouse monoclonal antibody is specific for myosin regulatory light chain 2. It is affinity purified by protein A. It can be applied to WB, IF, IHC and Indirect ELISA assays of myosin regulatory light chain 2.
Specifications
Target Information
Porcine myosin regulatory light chain 2 (MYL2) is a pivotal component of the myosin molecule that plays a crucial role in muscle contraction. As part of the myosin head, MYL2 interacts with the myosin heavy chain to form the motor unit of the myosin molecule, which is essential for the cross-bridge cycling that generates force during muscle contraction. Phosphorylation of MYL2 by myosin light chain kinase (MLCK) is a key regulatory mechanism that affects muscle contraction velocity and force. This post-translational modification increases the actin-activated MgATPase activity of myosin, enhancing the rate of cross-bridge cycling and thus influencing the speed and force of muscle contraction.
Shipping and Storage
This product is shipped with ice gel packs. Store at -80°C on receipt.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Margossian, Sarkis S. "Reversible dissociation of dog cardiac myosin regulatory light chain 2 and its influence on ATP hydrolysis." Journal of Biological Chemistry 260.25 (1985): 13747-13754.