Mouse Anti-Porcine SERPINE1 Mrna Binding Protein 1 (SERBP1) Monoclonal Antibody

Porcine SERPINE1 mRNA binding protein 1 (pSERBP1) is an RNA-binding protein that plays a crucial role in mRNA maturation and translational regulation. This protein is known to contain two RG/RGG repeat regions, which are involved in RNA binding, although it lacks other recognizable RNA-binding motifs. SERBP1 was initially identified as a hyaluronic acid binding protein, but recent studies have highlighted its central role in brain function and development, particularly in neurogenesis and synaptogenesis. In pigs, SERBP1 may be involved in the modulation of key biological processes such as translation regulation and mRNA processing, which are essential for maintaining cellular homeostasis. The protein's dysfunction has been linked to various diseases, including cancer and neurodegenerative disorders. Structural characterizations reveal that SERBP1 is an intrinsically disordered protein with atypical RNA binding modes, suggesting its dynamic interaction with RNA and potential role in diverse cellular processes.