Mouse Anti-Porcine TNFRSF1A-Associated Via Death Domain (TRADD) Monoclonal Antibody

Porcine TNFRSF1A, also known as porcine tumor necrosis factor receptor superfamily member 1A, plays a critical role in regulating immune responses and cellular activities. This receptor is particularly known for its involvement in the death domain signaling pathway, which is essential for the transmission of apoptotic signals within cells. As a target, Porcine TNFRSF1A interacts with various intracellular proteins, including those that contain death domains. One of its key interactions is with the adaptor protein TRADD (TNF receptor-associated death domain protein), which initiates signaling cascades leading to the activation of transcription factors such as NF-κB and AP-1, or the activation of apoptosis-mediating caspases.