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Mouse Anti-Swine CD163 Monoclonal Antibody

Cat. No.VD10H28

Product TypeAnimal-targeted Antibodies

Size

Product Overview

O12H28 monoclonal antibody is specific for Swine CD163, also know as Swine MM130 or SCARI1. It was purified by affinity chromatography on Protein A from tissue culture supernatant. It can be applied for Flow Cytometry (FC); Immunohistochemical (IHC); Immunofluorescence (IF); Immunoprecipitation (IP) and Western Blot (WB) .

Specifications

Application FC; IHC; IF; IP; WB
Clonality Monoclonal Antibody
Classification Primary Antibody
Clone O12H28
Host Mouse
Target Species Swine
Species Reactivity Swine
Specificity Swine CD163
Isotype IgG1
Immunogen Swine alveolar macrophages
Purification Protein A Purified
Purity ≥ 90% (SDS-PAGE)
Concentration 1.0 mg/mL
Conjugation Unconjugated
Preservative and Stabilizer 0.09% Sodium azide (NaN3)
Buffer Phosphate buffered saline
Physical State Liquid

Target Information

Cluster of differentiation 163 (CD163) is a scavenger receptor, a member of the cysteine-rich family, which is a monocyte/macrophage-specific membrane marker. CD163 is considered a marker of alternatively activated or anti-inflammatory macrophages. Swine CD163 is a major determinant for the entry of porcine reproductive and respiratory syndrome virus (PRRSV). CD163 functions as innate immune sensor for gram-positive and gram-negative bacteria.

Target Swine CD163
Target Synonym M130; MM130; SCARI1; CD163 molecule
Gene ID 397031
UniProt ID Q2VL90

Shipping and Storage

This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt (up to 12 months).

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

User Note

  1. Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.

References

  1. Johnsson, Martin, et al. "Sequence variation, evolutionary constraint, and selection at the CD163 gene in pigs." Genetics Selection Evolution 50 (2018): 1-9.
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