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Recombinant Bovine Toll Like Receptor 4 (TLR4), N-His
Product Overview
BioVenic's Recombinant Bovine Toll Like Receptor 4 (TLR4), N-His is a recombinant protein expressed from E.coli. Its predicted molecular weight is N/A. The purity is>97% (SDS-PAGE).
Specifications
Target Information
Bovine toll-like receptor 4 (TLR4) is a crucial protein involved in the innate immune system of mammals, including Bovines. It is a pattern recognition receptor that recognizes conserved molecular structures found in pathogens, known as pathogen-associated molecular patterns (PAMPs). Specifically, TLR4 is known to bind to lipopolysaccharide (LPS) found on the outer membrane of Gram-negative bacteria, initiating a signaling cascade that leads to the activation of the immune response.
Shipping and Storage
This product is shipped with dry ice. It is recommended to aliquot as needed and store at -80°C upon receipt. Reconstituted protein solution can be stored at 4°C for 1 week, at < -80°C for 12 months. Avoid repeated freezing and thawing.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Aliquot the reconstituted solution to minimise freeze-thaw cycles.