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Recombinant Canine C-X-C Motif Chemokine Ligand 13 (CXCL13), N-His
Product Overview
BioVenic's Recombinant Canine C-X-C Motif Chemokine Ligand 13 (CXCL13), N-His is a recombinant protein expressed from E.coli. Its predicted molecular weight is 12.1 kDa. The purity is>95% (SDS-PAGE).
Specifications
Target Information
C-X-C motif chemokine ligand 13 is encoded by the CXCL13 gene in dogs. Research has shown that natural infection with Leishmania infantum is associated with the impairment of follicular dendritic cells, CXCL13 expression, B cell migration and germinal center formation and associates these changes with severe clinical forms of visceral leishmaniasis.
Shipping and Storage
This product is shipped with dry ice. Avoid repeated freezing and thawing. Store for 12 months at -20°C or -80°C.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Aliquote the reconstituted solution to minimise freeze-thaw cycles.
References
- Silva, J. S. et al. Low CXCL13 expression, splenic lymphoid tissue atrophy and germinal center disruption in severe canine visceral leishmaniasis. PloS one. 2012, 7: e29103.