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Recombinant Clostridium perfringens Perfringolysin O (pfo), N-His

Name: Recombinant Clostridium perfringens Perfringolysin O (pfo), N-His
SKU: VG9C211
Rating: 5 (1 reviews)

Cat. No.VG9C211

Product TypeVeterinary Antigens

Size

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Product Overview

BioVenic's Recombinant Clostridium perfringens Perfringolysin O (pfo), N-His is a recombinant protein expressed from E.coli. Its predicted molecular weight is 54.9 kDa. The purity is>90% (SDS-PAGE).

Specifications

Type Recombinant Protein

Species Bacterium

Expression System E.coli

Purity >90% (SDS-PAGE)

Predicted Molecular Weight 54.9 kDa

Physical State Lyophilized

Formulation The buffer before lyophilization is a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.

Target Information

Clostridium perfringens perfringolysin O is a potent toxin that plays a critical role in the pathogenesis of diseases such as gas gangrene and necrotic enteritis in animals. In veterinary medicine, PFO's function as a cholesterol-dependent cytolysin makes it a key factor in causing cytotoxicity and inflammation, leading to tissue damage and contributing to the severity of infections. Understanding PFO is essential for developing strategies to prevent and treat clostridial diseases in animals.

Protein Clostridium perfringens Perfringolysin O (pfo)

Protein Synonym Theta-toxin; Thiol-activated cytolysin

UniProt ID P0C2E9

Shipping and Storage

This product is shipped with dry ice. Avoid repeated freezing and thawing. Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use.

Documents

Datasheet

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

User Note

Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.Aliquote the reconstituted solution to minimise freeze-thaw cycles.