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Recombinant Mouse Programmed Cell Death 1 Ligand 1 (CD274), C-Fc

Cat. No.AP2C844

Product TypeAnimal Proteins

Size

Product Overview

BioVenic's Recombinant Mouse Programmed Cell Death 1 Ligand 1 (CD274), C-Fc is a recombinant protein expressed from Human Cells. Its predicted molecular weight is 33.3 kDa. The purity is>90%.

Specifications

Type Recombinant Protein
Species Mouse
Expression System Human Cells
Purity >90%
Endotoxin < 1.0 EU/μg
Predicted Molecular Weight 33.3 kDa
Physical State Lyophilized
Formulation 0.01 mol/L PBS (pH 7.2) containing 0.2% (w/v) Procline-300.

Target Information

Mouse Programmed Cell Death 1 Ligand 1 (CD274) is a protein expressed on various immune cells and some non-immune cells. CD274 binds to PDCD1 on T cells, delivering inhibitory signals that suppress T cell function. This interaction is crucial for maintaining immune homeostasis and preventing excessive immune responses. CD274 is a central target in cancer immunotherapy, where inhibitors of this pathway have shown significant efficacy in enhancing tumor-specific immune responses.

Protein Mouse Programmed Cell Death 1 Ligand 1 (CD274)
Protein Synonym PD-L1; PDCD1 ligand 1; Programmed death ligand 1; hPD-L1
Gene ID 60533
UniProt ID Q9NZQ7

Shipping and Storage

This product is shipped with ice packs. Lyophilized protein can be stored at -20°C for 1 year. After reconstitution, the protein solution can be stored at 2-8°C for 2-7 days.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

User Note

  1. Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Aliquot the reconstituted solution to minimize freeze-thaw cycles.
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