Recombinant Mouse T-Lymphocyte Activation Antigen CD86 (CD86), C-His

Mouse T-Lymphocyte Activation Antigen CD86, or CD86, is an activation antigen expressed on antigen-presenting cells, involved in T lymphocyte activation and immune response regulation. In mouse models, CD86 is used to study its mechanisms in initiating and modulating immune responses. CD86 interacts with CD28 on T cells to provide essential costimulatory signals for T cell activation, proliferation, and differentiation. This interaction is crucial for the development of effective immune responses against pathogens. In cancer immunotherapy, CD86 has been explored as a target to enhance the activation of tumor-specific T cells. Additionally, CD86 is involved in the regulation of immune tolerance, as its expression can be modulated to prevent excessive immune activation in autoimmune diseases.