Recombinant Newcastle Disease Virus Nucleoprotein (N), His

The nucleoprotein (N protein) of Newcastle Disease Virus (NDV) is one of the most abundant structural proteins in the virus particle. It primarily functions to encapsidate the viral RNA genome for transcription, replication, and packaging. The N protein is highly conserved and immunogenic, making it an important target for developing diagnostic reagents and vaccines for NDV. In veterinary medicine, the N protein is used to develop diagnostic tools due to its ability to induce specific antibodies, serving as a key marker for detecting NDV infection. Additionally, the N protein can be used as a basis for vaccine development to induce protective immune responses against Newcastle disease. Studies on the structure and function of the N protein help to understand the infection mechanism of NDV, providing theoretical support for the prevention and control of Newcastle disease.