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Recombinant Parainfluenza Virus 5 Hemagglutinin-Neuraminidase (HN), C-His
Product Overview
BioVenic's Recombinant Parainfluenza Virus 5 Hemagglutinin-Neuraminidase (HN), C-His is a recombinant protein expressed from Mammalian Cells. Its predicted molecular weight is 61.1 kDa. The purity is>90% (SDS-PAGE).
Specifications
Target Information
The Parainfluenza virus 5 hemagglutinin-neuraminidase (HN) can infect animals. The HN protein plays a crucial role in the viral infection process, binding to sialic acid receptors on host cell surfaces (hemagglutinin activity) and catalyzing the hydrolysis of sialic acid (neuraminidase activity), aiding in viral entry. Additionally, HN interacts with the fusion protein F to promote the fusion of viral and host cell membranes. In the veterinary field, research on HN protein helps in the development of vaccines and diagnostic reagents for parainfluenza viruses.
Shipping and Storage
This product is shipped with dry ice. Avoid repeated freezing and thawing. Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.Aliquote the reconstituted solution to minimise freeze-thaw cycles.
References
- Welch, Brett D, et al. Structure of the parainfluenza virus 5 (PIV5) hemagglutinin-neuraminidase (HN) ectodomain.PLoS pathogens. 2013, 9(8): e1003534.