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Recombinant Rhizopus delemar Invasin CotH3 (CotH3), N-His
Product Overview
BioVenic's Recombinant Rhizopus delemar Invasin CotH3 (CotH3), N-His is a recombinant protein expressed from E.coli. Its predicted molecular weight is 64.0 kDa. The purity is>90% (SDS-PAGE).
Specifications
Target Information
In the veterinary field, the function of Rhizopus delemar invasin CotH3 (CotH3) is primarily associated with its role as an invasive factor. CotH3 is a surface protein essential for the hyphal invasion of endothelial cells by R. delemar. Studies have shown that antibodies specific to CotH3 can inhibit the growth of R. delemar and reduce its invasion of an endothelial cell layer
. Furthermore, CotH3 has potential applications in vaccine development and immunotherapy strategies, as anti-CotH3 antibodies can enhance the phagocytic activity of host cells against the fungus, thereby increasing the host's resistance to mucormycosis.
Shipping and Storage
This product is shipped with dry ice. Avoid repeated freezing and thawing. Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.Aliquote the reconstituted solution to minimise freeze-thaw cycles.