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Goat Anti-Vesicular Stomatitis Virus (VSV) Glycoprotein Polyclonal Antibody
Product Overview
BioVenic goat polyclonal antibody is specific for vesicular stomatitis virus glycoprotein. It can be applied to ELISA, ICC, IHC and WB of vesicular stomatitis virus glycoprotein.
Specifications
Target Information
Vesicular stomatitis virus (VSV) is a negative-sense RNA virus known for its ability to cause vesicular diseases in livestock and occasionally in humans. The Glycoprotein (G protein) of VSV is a critical surface protein that plays a central role in the virus's attachment to host cells and subsequent entry. This protein is a prime target for antiviral strategies due to its essential function in the viral life cycle and its exposure on the virion surface, making it accessible to the host immune system. The G protein is heavily glycosylated, which contributes to its structural stability and helps evade host immune detection. It mediates the fusion of the viral envelope with the host cell membrane, a process necessary for viral entry. Targeting the G protein can potentially inhibit this fusion process, thereby preventing viral replication. Additionally, the G protein is a major immunogen, eliciting neutralizing antibodies that can provide protection against VSV infection.
Shipping and Storage
This product is shipped at ambient temperature. Store at 4°C (up to 12 months) on receipt.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Roche, Stéphane, et al. "Structures of vesicular stomatitis virus glycoprotein: membrane fusion revisited." Cellular and molecular life sciences 65 (2008): 1716-1728.