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Rabbit Anti-Borrelia burgdorferi DbpA Polyclonal Antibody

Cat. No.VD7N108

Product TypeVeterinary Antibodies

Size

Product Overview

BioVenic rabbit polyclonal antibody is specific for Borrelia burgdorferi DbpA. It is affinity purified by protein A. It can be applied to ELISA and WB of Borrelia burgdorferi DbpA.

Specifications

Application ELISA; WB
Clonality Polyclonal
Classification Primary Antibody
Clone L12N56
Host Rabbit
Target Species Bacteria
Species Reactivity Bacteria
Specificity Borrelia burgdorferi DbpA Protein
Isotype IgG
Immunogen Recombinant Borrelia burgdorferi DbpA protein
Purification Protein A Purified
Purity > 90%
Conjugation Unconjugated
Preservative and Stabilizer 0.01% Sodium Azide
Buffer 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Physical State Liquid

Target Information

Borrelia burgdorferi DbpA, or decorin-binding protein A, is a surface lipoprotein that plays a significant role in the bacterium's pathogenesis and host interaction. DbpA is expressed during the tick phase of the bacterium's life cycle and is involved in the initial attachment of Borrelia burgdorferi to the tick vector and subsequent transmission to the mammalian host. This protein has the ability to bind decorin, a component of the extracellular matrix, which is crucial for the bacterium's adherence to tick tissues and its traversal through the tick's gut. DbpA's interaction with decorin also helps the bacterium to avoid the host's immune response, contributing to its stealth within the host.

Target Borrelia burgdorferi DbpA Protein
Taxonomy ID 139
Gene ID 56568603
UniProt ID O50917

Shipping and Storage

This product is shipped with ice gel packs. Store at -20°C (up to 12 months) on receipt. Avoid repeated freezing and thawing as this may denature the antibody.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

  1. Brown, Eric L., et al. "Adherence of Borrelia burgdorferi: identification of critical lysine residues in DbpA required for decorin binding." Journal of Biological Chemistry 274.37 (1999): 26272-26278.
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