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Mouse Anti-Bovine Caspase 8 (CASP8) Monoclonal Antibody
Product Overview
BioVenic mouse monoclonal antibody is specific for bovine caspase 8. It is affinity purified by protein A/G. It can be applied to WB, IHC and IF/ICC assays of bovine caspase 8.
Specifications
Target Information
Bovine caspase 8 is a key cysteine-aspartic protease involved in both apoptosis and non-apoptotic cellular functions. As an initiator caspase, it plays a central role in the extrinsic apoptotic pathway, activated by death receptors such as Fas or TNF-α receptors. Caspase 8 forms the death-inducing signaling complex (DISC), cleaving downstream effector caspases (e.g., caspase-3, -6, -7) to execute apoptosis. Besides apoptosis, Caspase 8 also regulates inflammation by activating the NLRP3 inflammasome and modulating immune responses.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.