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Mouse Anti-Canine Cyp7b1 Monoclonal Antibody

Cat. No.VD11N206

Product TypeAnimal-targeted Antibodies

Size 100 μL

Product Overview

BioVenic mouse monoclonal antibody is specific for canine Cyp7b1. It can be applied to WB assay of canine Cyp7b1.

Specifications

Application WB
Clonality Monoclonal
Classification Primary Antibody
Clone S18N1
Host Mouse
Target Species Canine
Species Reactivity Canine
Specificity Canine Cyp7b1
Isotype IgG2
Immunogen Recombinant protein of Cyp7b1
Concentration 0.63 mg/mL
Conjugation Unconjugated
Preservative and Stabilizer 0.02% Sodium Azide
Buffer Phosphate Buffered Saline, 1% BSA, 50% Glycerol
Physical State Liquid

Target Information

Canine CYP7B1 is a microsomal enzyme belonging to the cytochrome P450 family, which plays a significant role in the metabolism of steroids and oxysterols. It is involved in the 6α- or 7α-hydroxylation of several steroids and oxysterols, contributing to primary bile salt synthesis, steroid hormone metabolism, and immunoglobulin production. In dogs, CYP7B1 may be particularly important for maintaining the quiescence-activation balance of mesenchymal stem cells (MSCs), which is crucial for their therapeutic potential in conditions like arthritis. Additionally, CYP7B1 has been implicated in neuroinflammation, with CYP7B1 deficiency impairing myeloid cell activation in autoimmune disease of the central nervous system.

Target Canine Cyp7b1
Target Synonym Cytochrome P450 family 7 subfamily B member 1
Gene ID 486973
UniProt ID A0A8C0NFX8

Shipping and Storage

This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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