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Rabbit Anti-Canine Hepatocyte Growth Factor (HGF) Polyclonal Antibody

Cat. No.VD11N926

Product TypeAnimal-targeted Antibodies

Size

Product Overview

BioVenic rabbit polyclonal antibody is specific for canine hepatocyte growth factor. It is affinity purified by protein A. It can be applied to WB, IHC and IF/ICC assays of canine hepatocyte growth factor.

Specifications

Application WB; IHC; IF/ICC
Clonality Polyclonal
Classification Primary Antibody
Clone J20N14
Host Rabbit
Target Species Canine
Species Reactivity Canine
Specificity Canine Hepatocyte Growth Factor
Isotype IgG
Immunogen Recombinant protein of hepatocyte growth factor
Purification Protein A Purified
Concentration 0.58 mg/mL
Conjugation Unconjugated
Preservative and Stabilizer 0.05% Proclin 300
Buffer 0.01M Phosphate Buffered Saline, pH 7.4, 50% Glycerol
Physical State Liquid

Target Information

Canine hepatocyte growth factor (HGF) is a multifunctional heterodimeric glycoprotein synthesized and secreted by cells of mesenchymal origin, targeting epithelial and endothelial cells through endocrine and paracrine mechanisms. It activates a tyrosine kinase signaling cascade via the c-MET receptor, inducing cellular responses such as proliferation, motility, morphogenesis, and anti-apoptotic activities. These functions are essential for embryonic development, tissue regeneration, and repair in organs like the liver, kidneys, heart, and neural tissues. In dogs, HGF is particularly important for liver regeneration, as it stimulates hepatocyte proliferation and supports liver function in conditions such as chronic inflammation, cirrhosis, and congenital liver diseases.

Target Canine Hepatocyte Growth Factor
Target Synonym HGF
Gene ID 403441
UniProt ID Q867B7

Shipping and Storage

This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

  1. Balkovetz, Daniel F., et al. "Hepatocyte growth factor alters the polarity of Madin-Darby canine kidney cell monolayers." Journal of Biological Chemistry 272.6 (1997): 3471-3472.
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