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Mouse Anti-Canine General Transcription Factor IIH Subunit 1 (TFIIH1) Monoclonal Antibody

Cat. No.VD12N433

Product TypeAnimal-targeted Antibodies

Size 100 μL

Product Overview

BioVenic mouse monoclonal antibody is specific for canine general transcription factor IIH subunit 1. It is purified by affinity chromatography. It can be applied to WB assay of canine general transcription factor IIH subunit 1.

Specifications

Application WB
Clonality Monoclonal
Classification Primary Antibody
Clone M5N47
Host Mouse
Target Species Canine
Species Reactivity Canine
Specificity Canine General Transcription Factor IIH Subunit 1
Immunogen Recombinant protein of general transcription factor IIH subunit 1
Purification Purified by Affinity Chromatography
Concentration 1 mg/mL
Conjugation Unconjugated
Preservative and Stabilizer 0.02% Sodium Azide
Buffer 0.1M Tris-Glycine, pH 7.4, with 150 mM NaCl and 50% glycerol
Physical State Liquid

Target Information

Canine General Transcription Factor IIH Subunit 1 (GTF2H1) is a core component of the TFIIH complex, essential for transcription initiation and elongation by RNA polymerase II. It plays a crucial role in the phosphorylation of the RNA polymerase II C-terminal domain, facilitating the transition from transcription initiation to elongation. GTF2H1 is also involved in nucleotide excision repair, highlighting its dual function in transcription and DNA repair processes. This protein is localized in the nucleus and is widely expressed in various tissues.

Target Canine General Transcription Factor IIH Subunit 1
Target Synonym TFIIH p62
Gene ID 476881
UniProt ID A0A8I3NYI3

Shipping and Storage

This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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