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Mouse Anti-Clostridium difficile Glutamate Dehydrogenase (GDH) Monoclonal Antibody-Detection
Product Overview
BioVenic mouse monoclonal antibody is specific for Clostridium difficile GDH. It is affinity purified by protein A. It can be applied to ELISA assays of Clostridium difficile GDH. The clone L9N36 can be used as capture antibody and the L9N37 can be used as detection antibody in the ELISA assay.
Specifications
Target Information
Clostridium difficile is a Gram-positive, spore-forming bacterium that is a significant cause of antibiotic-associated diarrhea and pseudomembranous colitis. Glutamate dehydrogenase (GDH) is a key enzyme in C. difficile's metabolism and has emerged as an important diagnostic target for this pathogen. GDH plays a crucial role in the metabolic pathways of C. difficile, particularly in the conversion of glutamate to α-ketoglutarate and ammonia, which is essential for the bacterium's survival and growth.
Shipping and Storage
This product is shipped with ice gel packs. Store at -20°C (up to 12 months) on receipt. Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Recommended pairs for sandwich immunoassay (capture-detection): L9N36-L9N37
References
- Girinathan, Brintha Parasumanna, et al. "Importance of glutamate dehydrogenase (GDH) in Clostridium difficile colonization in vivo." Plos one 11.7 (2016): e0160107.