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Rabbit Anti-Borrelia burgdorferi OspB Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for Borrelia burgdorferi OspB. It is affinity purified by protein A. It can be applied to ELISA and WB of Borrelia burgdorferi OspB.
Specifications
Target Information
Borrelia burgdorferi OspB, or outer surface protein B, is a lipoprotein that plays a critical role in the bacterium's adherence and survival within Ixodes ticks, which are the vectors for Lyme disease transmission. OspB is expressed during the tick phase of the bacterium's life cycle and is essential for its ability to colonize the tick gut. This protein is implicated in the bacterium's evasion of the host's immune system and contributes to its infectivity. Studies have shown that OspB antibodies can prevent B. burgdorferi colonization of Ixodes scapularis, indicating its importance in the bacterium's interaction with the tick vector.
Shipping and Storage
This product is shipped with ice gel packs. Store at -20°C (up to 12 months) on receipt. Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Neelakanta, Girish, et al. "Outer surface protein B is critical for Borrelia burgdorferi adherence and survival within Ixodes ticks." PLoS Pathogens 3.3 (2007): e33.