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Mouse Anti-Foot-and-Mouth Disease Virus (FMDV) Serotype A Monoclonal Antibody

Product Overview

BioVenic mouse monoclonal antibody is specific for foot-and-mouth disease virus serotype A. It is affinity purified by ion-exchange. It can be applied to ELISA assays of foot-and-mouth disease virus serotype A.

Specifications

Application ELISA

Clonality Monoclonal

Classification Primary Antibody

Clone L9N8

Host Mouse

Target Species Virus

Species Reactivity Swine

Specificity Foot-and-Mouth Disease Virus Serotype A

Isotype IgG

Immunogen Inactivated foot-and-mouth disease virus serotype A

Purification Ion-Exchange Affinity Purified

Purity > 90%

Conjugation Unconjugated

Physical State Liquid

Target Information

Foot-and-mouth disease virus (FMDV) serotype A is a globally significant pathogen responsible for substantial economic losses in the livestock industry. This virus is known for its rapid transmission and ability to cause acute vesicular diseases in cloven-hoofed animals, leading to significant drops in productivity and trade restrictions. The target information for FMDV Serotype A centers on its capsid proteins, which are crucial for the virus's infectivity and host immune response. The four structural proteins-VP1, VP2, VP3, and VP4-form the viral capsid and are key antigenic sites for neutralizing antibodies. VP1, in particular, is the most variable and immunodominant protein, making it a primary focus for vaccine development and a target for immune responses.

Target Foot-and-Mouth Disease Virus Serotype A

Target Synonym FMDV; Aphthovirus A

Taxonomy ID 12111

Gene ID 3293263

UniProt ID P03306

Shipping and Storage

This product is shipped at ambient temperature. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.

Documents

Datasheet

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

Li, Kun, et al. "Conserved antigen structures and antibody-driven variations on foot-and-mouth disease virus serotype A revealed by bovine neutralizing monoclonal antibodies." PLoS Pathogens 19.11 (2023): e1011811.