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Mouse Anti-Nipah Virus Fusion Protein F2 Monoclonal Antibody
Product Overview
BioVenic mouse monoclonal antibody is specific for nipah virus fusion protein F2. It is affinity purified by protein A. It can be applied to IP and WB assays of nipah virus fusion protein F2.
Specifications
Target Information
The nipah virus fusion protein F2 chain, a cleavage product of the F0 precursor, is an integral part of the viral fusion machinery. The F2 chain is responsible for the structural stability and function of the fusion protein, which is essential for the virus's ability to merge its envelope with the host cell membrane. This process is critical for the delivery of the viral genome into the host cell, facilitating infection. The F2 chain, along with the F1 chain, forms the trimeric fusion protein complex, where the F1 chain is involved in the initial interaction with the host cell receptor. The F2 chain provides support to the F1 chain, maintaining its conformation and facilitating the necessary structural changes that lead to membrane fusion.
Shipping and Storage
This product is shipped at ambient temperature. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Byrne, Patrick O., et al. "Structural basis for antibody recognition of vulnerable epitopes on Nipah virus F protein." Nature Communications 14.1 (2023): 1494.