Rabbit Anti-Adeno Associated Virus (AAV) Polyclonal Antibody

Adeno-associated viruses (AAVs) are small, non-enveloped viruses that are widely used as vectors in gene therapy due to their low pathogenicity and ability to integrate into the host genome without causing disease. AAVs are particularly valuable for their broad tropism, meaning they can infect a variety of cell types, and their potential for long-term gene expression. The capsid of AAVs, composed of proteins VP1, VP2, and VP3, is a primary target for modification to enhance the virus's therapeutic properties. The capsid proteins determine the specificity of the virus for different cell types and its resistance to the host immune system. By altering these proteins, researchers can modify the tropism of AAVs to target specific tissues more effectively and reduce immunogenicity.