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Mouse Anti-Porcine Endogenous Retrovirus (PERV) Monoclonal Antibody
Product Overview
BioVenic mouse monoclonal antibody is specific for porcine endogenous retrovirus. It is affinity purified by protein A. It can be applied to WB and ELISA assays of porcine endogenous retrovirus.
Specifications
Target Information
The porcine endogenous retrovirus type A (PERV-A) envelope glycoprotein is a key component of the viral envelope, which is crucial for the infection process of PERV-A. This glycoprotein is responsible for the binding and fusion of the virus with target cells, enabling the transmission of the viral genome into the host cell. The PERV-A envelope glycoprotein is derived from the viral genome and is expressed on the surface of infected cells, where it plays a pivotal role in the viral life cycle. As a target for antiviral strategies, the PERV-A envelope glycoprotein presents an opportunity for intervention due to its critical involvement in the initial stages of viral infection. Inhibiting the function of this glycoprotein could prevent the virus from binding to and entering host cells, thereby limiting the spread of infection. The development of monoclonal antibodies or small molecule inhibitors that target the PERV-A envelope glycoprotein may offer a means to disrupt the virus's entry mechanism.
Shipping and Storage
This product is shipped at ambient temperature. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Mattiuzzo, Giada, et al. "Differential resistance to cell entry by porcine endogenous retrovirus subgroup A in rodent species." Retrovirology 4 (2007): 1-13.