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Mouse Anti-Porcine Endogenous Retrovirus (PERV) Monoclonal Antibody

Cat. No.VD7N195

Product TypeVeterinary Antibodies

Size

Product Overview

BioVenic mouse monoclonal antibody is specific for porcine endogenous retrovirus. It is affinity purified by protein A. It can be applied to WB and ELISA assays of porcine endogenous retrovirus.

Specifications

Application WB; ELISA
Clonality Monoclonal
Classification Primary Antibody
Clone L16N23
Host Mouse
Target Species Virus
Species Reactivity Virus
Specificity Porcine Endogenous Retrovirus Type A Envelope Glycoprotein
Isotype IgG2
Immunogen Recombinant porcine endogenous retrovirus type A envelope glycoprotein
Purification Protein A Purified
Purity > 90%
Concentration 1 mg/mL
Conjugation Unconjugated
Preservative and Stabilizer 0.02% Proclin 300
Buffer Phosphate Buffered Saline
Physical State Liquid

Target Information

The porcine endogenous retrovirus type A (PERV-A) envelope glycoprotein is a key component of the viral envelope, which is crucial for the infection process of PERV-A. This glycoprotein is responsible for the binding and fusion of the virus with target cells, enabling the transmission of the viral genome into the host cell. The PERV-A envelope glycoprotein is derived from the viral genome and is expressed on the surface of infected cells, where it plays a pivotal role in the viral life cycle. As a target for antiviral strategies, the PERV-A envelope glycoprotein presents an opportunity for intervention due to its critical involvement in the initial stages of viral infection. Inhibiting the function of this glycoprotein could prevent the virus from binding to and entering host cells, thereby limiting the spread of infection. The development of monoclonal antibodies or small molecule inhibitors that target the PERV-A envelope glycoprotein may offer a means to disrupt the virus's entry mechanism.

Target Porcine Endogenous Retrovirus Type A Envelope Glycoprotein
Target Synonym Porcine Endogenous Retrovirus C; Type A PERV Env Protein; Env
Taxonomy ID 194958
UniProt ID A7UMV0

Shipping and Storage

This product is shipped at ambient temperature. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

  1. Mattiuzzo, Giada, et al. "Differential resistance to cell entry by porcine endogenous retrovirus subgroup A in rodent species." Retrovirology 4 (2007): 1-13.
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