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Mouse Anti-Monkeypox Virus A35R Monoclonal Antibody

Cat. No.VD7N208

Product TypeVeterinary Antibodies

Size 100 µg

Product Overview

BioVenic mouse monoclonal antibody is specific for monkeypox virus A35R. It is affinity purified by protein A and protein G. It can be applied to ELISA, IFA, FACS, WB and ICA assays of monkeypox virus A35R.

Specifications

Application ELISA; IFA; FACS; WB; ICA
Clonality Monoclonal
Classification Primary Antibody
Clone G1N13
Host Mouse
Target Species Virus
Species Reactivity Virus
Specificity Monkeypox A35R
Isotype IgG2
Immunogen Recombinant monkeypox A35r
Purification Protein A/G Mix Purified
Purity > 90%
Conjugation Unconjugated
Buffer 0.02µM Phosphate Buffered Saline, pH 7.4
Physical State Liquid

Target Information

The Monkeypox virus A35R protein is a significant immunomodulatory factor that plays a role in the pathogenesis of the virus. A35R is a homolog of the human IL-17 receptor and is thought to interfere with the host's immune response by mimicking host cytokine receptors, potentially dampening the inflammatory response and aiding in viral evasion. As a target for antiviral strategies, A35R presents a unique opportunity for intervention. By understanding its interaction with the host immune system, researchers can develop therapeutics that counteract its immunosuppressive effects. Inhibiting A35R's function could enhance the host's ability to mount an effective immune response against the virus, limiting its replication and spread.

Target Monkeypox A35R
Taxonomy ID 10244
UniProt ID Q8V4U4

Shipping and Storage

This product is shipped with wet ice packs. Store at -20°C on receipt (up to 24 months). Avoid exposure to light. Avoid repeated freezing and thawing as this may denature the antibody.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

  1. Qu, Jing, et al. "A Comparative Evaluation of Three Diagnostic Assays for the Detection of Human Monkeypox." Viruses 16.8 (2024): 1286.
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