This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Mouse Anti-Monkeypox Virus A35R Monoclonal Antibody
Product Overview
BioVenic mouse monoclonal antibody is specific for monkeypox virus A35R. It is affinity purified by protein A and protein G. It can be applied to ELISA, IFA, FACS, WB and ICA assays of monkeypox virus A35R.
Specifications
Target Information
The Monkeypox virus A35R protein is a significant immunomodulatory factor that plays a role in the pathogenesis of the virus. A35R is a homolog of the human IL-17 receptor and is thought to interfere with the host's immune response by mimicking host cytokine receptors, potentially dampening the inflammatory response and aiding in viral evasion. As a target for antiviral strategies, A35R presents a unique opportunity for intervention. By understanding its interaction with the host immune system, researchers can develop therapeutics that counteract its immunosuppressive effects. Inhibiting A35R's function could enhance the host's ability to mount an effective immune response against the virus, limiting its replication and spread.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 24 months). Avoid exposure to light. Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Qu, Jing, et al. "A Comparative Evaluation of Three Diagnostic Assays for the Detection of Human Monkeypox." Viruses 16.8 (2024): 1286.