Mouse Anti-Severe Fever and Thrombocytopenic Syndrome Virus (SFTSV) Monoclonal Antibody

Severe fever and thrombocytopenic syndrome virus (SFTSV) is an emerging pathogen that poses significant public health challenges. The glycoprotein N of SFTSV, also known as sGn, is a surface glycoprotein that is critical for the virus's ability to infect host cells. This protein is involved in the initial binding to host receptors and subsequent fusion of the viral envelope with the host cell membrane, enabling viral entry. The glycoprotein N is a promising target for antiviral development due to its role in the early stages of viral infection. It is immunogenic and can elicit a host immune response, suggesting its potential use in vaccine formulations. Moreover, the protein's involvement in receptor binding makes it an attractive target for therapeutic intervention, as disruption of this interaction could prevent viral attachment and entry.