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Rabbit Anti-Adeno Associated Virus (AAV) 5 VP3 Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for adeno associated virus 5 VP3. It can be applied to WB of adeno associated virus 5 VP3.
Specifications
Target Information
The capsid VP3 protein of adeno-associated virus 5 (AAV5) is a structural protein that forms the viral capsid, the protective shell of the virus. AAV5 is a promising vector for gene therapy due to its low immunogenicity and ability to efficiently transduce a variety of cell types. The VP3 protein, as part of the capsid, is instrumental in determining the tropism and transduction efficiency of the virus. The VP3 protein, along with other capsid proteins (VP1 and VP2), contributes to the overall structure and stability of the AAV5 capsid. It plays a role in the virus's resistance to degradation and its ability to bind to specific cell surface receptors, which is a critical step in the viral entry process. The unique properties of the VP3 protein, including its amino acid sequence and post-translational modifications, can influence the specificity of AAV5 for different tissues and cell types.
Shipping and Storage
This product is shipped with ice gel packs. Store at -20°C (up to 6 months) on receipt. Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Le, Dinh To, et al. "Adeno-associated virus capsid protein expression in Escherichia coli and chemically defined capsid assembly." Scientific Reports 9.1 (2019): 18631.