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Rabbit Anti-Dengue Virus prM Protein Polyclonal Antibody
Product Overview
BioVenic rabbit anti-Dengue virus prM protein polyclonal antibody can be used in ELISA and IF to help researchers detect or develop diagnosis assays of Dengue virus infection.
Specifications
Target Information
The prM protein is synthesized as part of a larger polyprotein during the Dengue virus replication process. After synthesis, it forms a precursor complex with the viral Envelope (E) protein. This complex is essential for the proper folding and assembly of the virus particles. The prM protein also acts as a chaperone, preventing the premature fusion of the virus with host cell membranes within the infected mosquito. The importance of the prM protein in diagnostic assay development lies in its potential as a target for detecting Dengue virus infections.
Shipping and Storage
This product is shipped with dry ice. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Hsieh, Szu-Chia, et al. "Highly conserved residues in the helical domain of dengue virus type 1 precursor membrane protein are involved in assembly, precursor membrane (prM) protein cleavage, and entry." Journal of Biological Chemistry 289.48 (2014): 33149-33160.