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Rabbit Anti-Severe Fever and Thrombocytopenic Syndrome Virus (SFTSV) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for severe fever and thrombocytopenic syndrome virus. It is affinity purified by protein A. It can be applied to IF of severe fever and thrombocytopenic syndrome virus.
Specifications
Target Information
Severe fever and thrombocytopenic syndrome virus (SFTSV) is an emerging pathogen that poses significant public health challenges. The glycoprotein N of SFTSV, also known as sGn, is a surface glycoprotein that is critical for the virus's ability to infect host cells. This protein is involved in the initial binding to host receptors and subsequent fusion of the viral envelope with the host cell membrane, enabling viral entry. The glycoprotein N is a promising target for antiviral development due to its role in the early stages of viral infection. It is immunogenic and can elicit a host immune response, suggesting its potential use in vaccine formulations. Moreover, the protein's involvement in receptor binding makes it an attractive target for therapeutic intervention, as disruption of this interaction could prevent viral attachment and entry.
Shipping and Storage
This product is shipped at ambient temperature. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Kim, Ki Hyun, et al. "An anti-Gn glycoprotein antibody from a convalescent patient potently inhibits the infection of severe fever with thrombocytopenia syndrome virus." PLoS Pathogens 15.2 (2019): e1007375.