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Rabbit Anti-Severe Fever and Thrombocytopenic Syndrome Virus (SFTSV) Polyclonal Antibody

Cat. No.VD7N200

Product TypeVeterinary Antibodies

Size

Product Overview

BioVenic rabbit polyclonal antibody is specific for severe fever and thrombocytopenic syndrome virus. It is affinity purified by protein A. It can be applied to IF of severe fever and thrombocytopenic syndrome virus.

Specifications

Application IF
Clonality Polyclonal
Classification Primary Antibody
Clone G1N5
Host Rabbit
Target Species Virus
Species Reactivity Virus
Specificity Severe Fever and Thrombocytopenic Syndrome Virus Glycoprotein N
Isotype IgG
Immunogen Inactivated severe fever and thrombocytopenic syndrome virus
Purification Protein A Purified
Purity > 90%
Concentration 1 mg/mL
Conjugation Unconjugated
Preservative and Stabilizer 0.02% Proclin 300
Buffer Phosphate Buffered Saline
Physical State Liquid

Target Information

Severe fever and thrombocytopenic syndrome virus (SFTSV) is an emerging pathogen that poses significant public health challenges. The glycoprotein N of SFTSV, also known as sGn, is a surface glycoprotein that is critical for the virus's ability to infect host cells. This protein is involved in the initial binding to host receptors and subsequent fusion of the viral envelope with the host cell membrane, enabling viral entry. The glycoprotein N is a promising target for antiviral development due to its role in the early stages of viral infection. It is immunogenic and can elicit a host immune response, suggesting its potential use in vaccine formulations. Moreover, the protein's involvement in receptor binding makes it an attractive target for therapeutic intervention, as disruption of this interaction could prevent viral attachment and entry.

Target Severe Fever and Thrombocytopenic Syndrome Virus Glycoprotein N
Target Synonym SFTS; Glycoprotein N; SFTSV Gn; Envelopment Polyprotein; Severe Fever and Thrombocytopenic Syndrome Virus; Arthropod-Bborne Phleboviruses; Guertu Virus; GTV; Heartland Virus; HRTV
Taxonomy ID 1003835

Shipping and Storage

This product is shipped at ambient temperature. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

  1. Kim, Ki Hyun, et al. "An anti-Gn glycoprotein antibody from a convalescent patient potently inhibits the infection of severe fever with thrombocytopenia syndrome virus." PLoS Pathogens 15.2 (2019): e1007375.
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