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Rabbit Anti-Borrelia burgdorferi CRASP-2 Polyclonal Antibody

Cat. No.VD7N107

Product TypeVeterinary Antibodies

Size

Product Overview

BioVenic rabbit polyclonal antibody is specific for Borrelia burgdorferi CRASP-2. It is affinity purified by protein A. It can be applied to ELISA and WB of Borrelia burgdorferi CRASP-2.

Specifications

Application ELISA; WB
Clonality Polyclonal
Classification Primary Antibody
Clone L12N55
Host Rabbit
Target Species Bacteria
Species Reactivity Bacteria
Specificity Borrelia burgdorferi CRASP-2 Protein
Isotype IgG
Immunogen Recombinant Borrelia burgdorferi CRASP-2 protein
Purification Protein A Purified
Purity > 90%
Conjugation Unconjugated
Preservative and Stabilizer 0.01% Sodium Azide
Buffer 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Physical State Liquid

Target Information

Borrelia burgdorferi CRASP-2, also known as BBA16 or an Elp (Erp-like) protein, is a member of the Erp (OspE/F-related) family of proteins in the bacterium that causes Lyme disease. CRASP-2 is expressed during the tick phase of the bacterium's life cycle, similar to CRASP-1, and contributes to its immune evasion strategies. This protein is implicated in the bacterium's ability to interact with the host environment and modulate the host's immune response. CRASP-2 may participate in the acquisition of complement regulators from the host, similar to its function as a surface protein that can bind to host proteins and potentially protect the bacterium from being cleared by the immune system.

Target Borrelia burgdorferi CRASP-2 Protein
Taxonomy ID 139
UniProt ID A9QVU8

Shipping and Storage

This product is shipped with ice gel packs. Store at -20°C (up to 12 months) on receipt. Avoid repeated freezing and thawing as this may denature the antibody.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

  1. Coleman, Adam S., et al. "Borrelia burgdorferi complement regulator-acquiring surface protein 2 does not contribute to complement resistance or host infectivity." Plos one 3.8 (2008): 3010e.
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