Rabbit Anti-Borrelia burgdorferi VlsE Polyclonal Antibody

Borrelia burgdorferi VlsE, or variable large surface protein E, is a key immunogenic protein of the bacterium that causes Lyme disease. VlsE is a member of the vlsE gene family, which is characterized by its ability to undergo antigenic variation, allowing the bacterium to evade the host's immune response. The VlsE protein is a lipoprotein that is expressed on the surface of the spirochete, making it a significant target for the host's immune system. It plays a crucial role in the bacterium's adaptation to its environment and contributes to its pathogenicity. The antigenic variation of VlsE is achieved through genetic recombination events within the vlsE gene, leading to the production of multiple protein variants that can confuse the host's immune recognition.