Mouse Anti-Chlamydia trachomatis Lipopolysaccharides (LPS) Monoclonal Antibody

Chlamydia trachomatis, a Gram-negative intracellular bacterium, is known for its ability to evade the host immune system, partly due to its unique lipopolysaccharides (LPS). LPS is a major component of the outer membrane of Gram-negative bacteria and plays a significant role in the pathogen's virulence and immune evasion. The LPS of Chlamydia trachomatis is structurally distinct from that of other bacteria, with modifications that reduce its immunogenicity. This allows the bacterium to dampen the host's inflammatory response, facilitating its intracellular survival and replication. The lipid A component of the LPS is particularly important for its endotoxic properties, which can trigger a cascade of immune responses if not effectively managed.