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Mouse Anti-Nipah Virus Fusion Protein Site II Monoclonal Antibody
Product Overview
BioVenic mouse monoclonal antibody is specific for nipah virus fusion protein site II. It is affinity purified by protein A. It can be applied to IP of nipah virus fusion protein site II.
Specifications
Target Information
The nipah virus fusion protein F2 possesses a second cleavage site, known as site II, which is distinct from the initial activation site (site I). Site II is involved in a subsequent cleavage event that can further modulate the activity of the F protein, although the exact role of this site in the nipah virus life cycle is not as well characterized as site I. Nonetheless, the presence of multiple cleavage sites within the F protein highlights the complexity of the viral fusion machinery and the potential for regulation at different stages of the infection process.
Shipping and Storage
This product is shipped at ambient temperature. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Aguilar, Hector C., et al. "A novel receptor-induced activation site in the Nipah virus attachment glycoprotein (G) involved in triggering the fusion glycoprotein (F)." Journal of Biological Chemistry 284.3 (2009): 1628-1635.