Mouse Anti-Vaccinia Virus Fusion Complex Associated Protein OPG095 Monoclonal Antibody

The vaccinia virus fusion complex associated protein OPG095, also referred to as F12L, is a critical component of the virus's fusion machinery. This protein is integral to the process by which the vaccinia virus fuses with the host cell membrane, allowing the viral core to be released into the cytoplasm. OPG095 is part of the fusion complex that includes other proteins such as H3L and A33R, which together mediate the membrane fusion event essential for viral entry. As a target for antiviral research, OPG095 presents a strategic point of intervention. Disrupting its function could potentially inhibit the fusion process, thereby preventing the virus from entering host cells and initiating infection. The detailed study of OPG095's structure and its interaction with other components of the fusion complex is vital for understanding the molecular mechanisms underlying viral fusion. Insights gained from such research could inform the development of antiviral agents that specifically target the fusion process, offering a new approach to combat the vaccinia virus and related poxviruses.