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Mouse Anti-Porcine Dickkopf Homolog 3 (DKK3) Monoclonal Antibody
Product Overview
BioVenic mouse monoclonal antibody is specific for dickkopf homolog 3. It is affinity purified by protein A. It can be applied to WB, IHC, IF and ELISA assays of dickkopf homolog 3.
Specifications
Target Information
Porcine dickkopf homolog 3 (DKK3) is a protein that belongs to the Dickkopf family, which is involved in the regulation of various developmental processes, particularly in the context of the porcine skeletal system. DKK3 plays a significant role in the Wnt signaling pathway, which is crucial for cell fate determination, tissue polarity, and the regulation of bone metabolism. This protein functions as an antagonist of the Wnt signaling pathway, inhibiting the activity of Wnt ligands and thus suppressing the signaling cascade that leads to the activation of target genes. DKK3's role in the modulation of Wnt signaling is essential for maintaining the balance between bone formation and resorption, as well as for the proper development of skeletal structures.
Shipping and Storage
This product is shipped with ice gel packs. Store at -20°C (up to 12 months) on receipt.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Gondkar, Kirti, et al. "Dickkopf homolog 3 (DKK3) acts as a potential tumor suppressor in gallbladder cancer." Frontiers in Oncology 9 (2019): 1121.