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Mouse Anti-Porcine Dickkopf Homolog 3 (DKK3) Monoclonal Antibody

Cat. No.VD8N327

Product TypeAnimal-targeted Antibodies

Size

Product Overview

BioVenic mouse monoclonal antibody is specific for dickkopf homolog 3. It is affinity purified by protein A. It can be applied to WB, IHC, IF and ELISA assays of dickkopf homolog 3.

Specifications

Application WB; IF; IHC; ELISA
Clonality Monoclonal
Classification Primary Antibody
Clone G7N2
Host Mouse
Target Species Porcine
Species Reactivity Porcine
Specificity Dickkopf Homolog 3
Isotype IgG2
Immunogen Recombinant protein of dickkopf homolog 3
Purification Protein A Purified
Concentration 1200 μg/mL
Conjugation Unconjugated
Preservative and Stabilizer 0.02% Sodium Azide
Buffer Phosphate Buffered Saline with 50% Glycerol, pH 7.3
Physical State Liquid

Target Information

Porcine dickkopf homolog 3 (DKK3) is a protein that belongs to the Dickkopf family, which is involved in the regulation of various developmental processes, particularly in the context of the porcine skeletal system. DKK3 plays a significant role in the Wnt signaling pathway, which is crucial for cell fate determination, tissue polarity, and the regulation of bone metabolism. This protein functions as an antagonist of the Wnt signaling pathway, inhibiting the activity of Wnt ligands and thus suppressing the signaling cascade that leads to the activation of target genes. DKK3's role in the modulation of Wnt signaling is essential for maintaining the balance between bone formation and resorption, as well as for the proper development of skeletal structures.

Target Dickkopf Homolog 3
Gene ID 664653
UniProt ID Q2HWR5

Shipping and Storage

This product is shipped with ice gel packs. Store at -20°C (up to 12 months) on receipt.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

  1. Gondkar, Kirti, et al. "Dickkopf homolog 3 (DKK3) acts as a potential tumor suppressor in gallbladder cancer." Frontiers in Oncology 9 (2019): 1121.
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