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Mouse Anti-Porcine Digeorge Syndrome Critical Region Gene 8 (DGCR8) Monoclonal Antibody
Product Overview
BioVenic mouse monoclonal antibody is specific for digeorge syndrome critical region gene 8. It is affinity purified by protein A. It can be applied to WB, IP and ELISA assays of digeorge syndrome critical region gene 8.
Specifications
Target Information
Porcine digeorge syndrome critical region gene 8 (DGCR8) is a gene that is conserved across mammalian species, including pigs, and plays a pivotal role in the regulation of gene expression. This gene is particularly important for its function in the microRNA (miRNA) biogenesis pathway. DGCR8 is involved in the processing of pri-miRNAs into pre-miRNAs, which are subsequently matured into functional miRNAs that can modulate the expression of target genes. In pigs, DGCR8 is a target of interest for research into developmental biology and genetic disorders. The study of DGCR8 can provide insights into the molecular mechanisms that govern growth, development, and the maintenance of tissue homeostasis. Given the role of miRNAs in a wide range of biological processes, including cell differentiation, apoptosis, and immune responses, DGCR8 is also implicated in various physiological and pathological conditions.
Shipping and Storage
This product is shipped with ice gel packs. Store at -20°C (up to 12 months) on receipt.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Chen, Zixuan, et al. "DiGeorge syndrome critical region 8 (DGCR8) protein-mediated microRNA biogenesis is essential for vascular smooth muscle cell development in mice." Journal of Biological Chemistry 287.23 (2012): 19018-19028.