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Mouse Anti-Porcine Digeorge Syndrome Critical Region Gene 8 (DGCR8) Monoclonal Antibody

Cat. No.VD8N250

Product TypeAnimal-targeted Antibodies

Size

Product Overview

BioVenic mouse monoclonal antibody is specific for digeorge syndrome critical region gene 8. It is affinity purified by protein A. It can be applied to WB, IP and ELISA assays of digeorge syndrome critical region gene 8.

Specifications

Application WB; IP; ELISA
Clonality Monoclonal
Classification Primary Antibody
Clone G5N63
Host Mouse
Target Species Porcine
Species Reactivity Porcine
Specificity Digeorge Syndrome Critical Region Gene 8
Isotype IgG2
Immunogen Recombinant protein of digeorge syndrome critical region gene 8
Purification Protein A Purified
Concentration 1600 μg/mL
Conjugation Unconjugated
Preservative and Stabilizer 0.02% Sodium Azide
Buffer Phosphate Buffered Saline with 50% Glycerol, pH 7.3
Physical State Liquid

Target Information

Porcine digeorge syndrome critical region gene 8 (DGCR8) is a gene that is conserved across mammalian species, including pigs, and plays a pivotal role in the regulation of gene expression. This gene is particularly important for its function in the microRNA (miRNA) biogenesis pathway. DGCR8 is involved in the processing of pri-miRNAs into pre-miRNAs, which are subsequently matured into functional miRNAs that can modulate the expression of target genes. In pigs, DGCR8 is a target of interest for research into developmental biology and genetic disorders. The study of DGCR8 can provide insights into the molecular mechanisms that govern growth, development, and the maintenance of tissue homeostasis. Given the role of miRNAs in a wide range of biological processes, including cell differentiation, apoptosis, and immune responses, DGCR8 is also implicated in various physiological and pathological conditions.

Target Digeorge Syndrome Critical Region Gene 8
Target Synonym C22orf12; DGCR8
Gene ID 100616094
UniProt ID F1RHN0

Shipping and Storage

This product is shipped with ice gel packs. Store at -20°C (up to 12 months) on receipt.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

  1. Chen, Zixuan, et al. "DiGeorge syndrome critical region 8 (DGCR8) protein-mediated microRNA biogenesis is essential for vascular smooth muscle cell development in mice." Journal of Biological Chemistry 287.23 (2012): 19018-19028.
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