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Mouse Anti-Equine CD8 Monoclonal Antibody-[FITC]

Cat. No.VD11N692

Product TypeAnimal-targeted Antibodies

Size 100 µg

Product Overview

BioVenic mouse monoclonal antibody is specific for equine CD8. It can be applied to FCM assay of equine CD8.

Specifications

Application FCM
Clonality Monoclonal
Classification Primary Antibody
Clone J7N38
Host Mouse
Target Species Equine
Species Reactivity Equine
Specificity Equine CD8
Isotype IgG1
Immunogen Recombinant protein of CD8
Concentration 0.1 mg/mL
Conjugation FITC
Preservative and Stabilizer Sodium Azide
Buffer Phosphate Buffered Saline, 1% BSA
Physical State Liquid

Target Information

Equine CD8 is a critical co-receptor expressed on a subset of T lymphocytes, primarily involved in the immune response against intracellular pathogens and tumor cells. It functions as a co-receptor with the T cell receptor (TCR) to recognize antigens presented by major histocompatibility complex class I (MHC-I) molecules. This interaction is essential for the activation of cytotoxic T lymphocytes (CTLs), which play a significant role in eliminating infected cells and maintaining immune surveillance. In horses, CD8+ T cells are crucial for defense against viral infections such as equine herpesvirus type 1, where they contribute to the clearance of the virus through the production of interferon-gamma and cytotoxic activity.

Target Equine CD8
Target Synonym T-cell surface glycoprotein CD8
Gene ID 100066774
UniProt ID F7BJE5

Shipping and Storage

This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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