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Mouse Anti-Porcine UDP-Galactose-4-Epimerase (GALE) Monoclonal Antibody
Product Overview
BioVenic mouse monoclonal antibody is specific for UDP-galactose-4-epimerase. It is affinity purified by protein A. It can be applied to WB and ELISA assays of UDP-galactose-4-epimerase.
Specifications
Target Information
Porcine UDP-galactose-4-epimerase, also known as GALE, is an enzyme that catalyzes the conversion of UDP-galactose to UDP-glucose, a reaction essential for the synthesis of glycogen and other glycoconjugates in cells. This epimerase plays a critical role in the metabolism of carbohydrates and the maintenance of cellular homeostasis, particularly in the liver and erythrocytes. As a molecular target, GALE is significant due to its involvement in the biosynthesis of glycoconjugates, which are crucial for various cellular functions, including cell signaling, immune response, and the structural integrity of cells. Disruptions in GALE activity can lead to metabolic disorders and have been associated with certain diseases, such as galactosemia, a genetic disorder characterized by the inability to metabolize galactose.
Shipping and Storage
This product is shipped with ice gel packs. Store at -20°C (up to 12 months) on receipt.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Daenzer, Jennifer MI, et al. "UDP-galactose 4'-epimerase activities toward UDP-Gal and UDP-GalNAc play different roles in the development of Drosophila melanogaster." PLoS genetics 8.5 (2012): e1002721.