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Rabbit Anti-Canine Thrombomodulin (THBD) Polyclonal Antibody

Cat. No.VD11N288

Product TypeAnimal-targeted Antibodies

Size

Product Overview

BioVenic rabbit polyclonal antibody is specific for canine thrombomodulin. It is affinity purified by protein A. It can be applied to WB, IHC and IF/ICC assays of canine thrombomodulin.

Specifications

Application WB; IHC; IF/ICC
Clonality Polyclonal
Classification Primary Antibody
Clone D17N25
Host Rabbit
Target Species Canine
Species Reactivity Canine
Specificity Canine Thrombomodulin
Immunogen Recombinant protein of thrombomodulin
Purification Protein A Purified
Conjugation Unconjugated
Preservative and Stabilizer 0.05% Proclin 300
Buffer 0.01M Phosphate Buffered Saline, pH 7.4, 50% Glycerol
Physical State Liquid

Target Information

Canine thrombomodulin (TM), encoded by the THBD gene, is a glycoprotein primarily located on endothelial cell surfaces and is a major regulator of vascular thromboresistance. It plays a crucial role in the anticoagulant process by binding thrombin and activating protein C, which inhibits the coagulation cascade. TM expression can be down-regulated in dogs with systemic inflammatory diseases, leading to an increased risk of thrombosis and disseminated intravascular coagulation. This protein is essential for maintaining vascular homeostasis and has anticoagulant, anti-inflammatory, and cytoprotective properties.

Target Canine Thrombomodulin
Target Synonym THBD
Gene ID 474355
UniProt ID Q5W7P8

Shipping and Storage

This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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