Rabbit Anti-Porcine Thymidine Kinase (pTK) Polyclonal Antibody

Porcine thymidine kinase (pTK) is a key enzyme involved in the salvage pathway of pyrimidine nucleotide biosynthesis. It catalyzes the transfer of a phosphate group from ATP to the 5'-hydroxyl group of thymidine, producing thymidine monophosphate (TMP), which is subsequently converted into thymidine diphosphate (TDP) and thymidine triphosphate (TTP). These active thymidine nucleotides are crucial for DNA replication and repair. pTK is highly conserved across species, reflecting its fundamental role in cellular metabolism. The study of pTK in pigs can provide insights into the regulation of DNA synthesis and its implications in various biological processes, including cell proliferation, differentiation, and apoptosis.