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Rabbit Anti-Swine CTLA-4 Polyclonal Antibody

Cat. No.VD10H75

Product TypeAnimal-targeted Antibodies

Size

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Product Overview

O17H75 polyclonal antibody is specific for Swine Cytotoxic T-lymphocyte-associated protein 4 (CTLA4), also known CD152. It was purified from whole serum by affinity chromatography. It can be applied for ELISA and Western Blot (WB).

Specifications

Application ELISA; WB

Clonality Polyclonal Antibody

Classification Primary Antibody

Clone O17H75

Host Rabbit

Target Species Swine

Species Reactivity Swine

Specificity Swine CTLA-4

Immunogen Recombinant Swine CTLA-4

Purification Affinity chromatography Purified

Purity ≥ 90% (SDS-PAGE)

Conjugation Unconjugated

Physical State Liquid

Target Information

Cytotoxic T-lymphocyte-associated protein 4 (CTLA4), also known as cluster of differentiation 152 (CD152) is a B7/CD28 family member that negatively regulates T cell responses. Expression of swine CTLA4-Ig resulted in acute susceptibility to opportunistic pathogens due at least in part to a significantly compromised humoral immune status. CTLA4 is a T lymphocyte surface protein with a major role in downregulation of the immune response.

Target Swine CTLA-4

Target Synonym CTLA4; ALPS5; CD; CD152; CELIAC3; CTLA-4; GRD4; GSE; IDDM12; cytotoxic T-lymphocyte associated protein 4

Gene ID 397286

UniProt ID Q9MYX7

Shipping and Storage

This product is shipped at ambient temperature. It is recommended to aliquot and store at 2-8C on receipt.

Documents

Datasheet

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

Tian, Min, et al. "Alternative immunomodulatory strategies for xenotransplantation: CD80/CD86-CTLA4 pathway-modified immature dendritic cells promote xenograft survival." PloS one 8.7 (2013): e69640.