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Recombinant Bovine Gastrin/Cholecystokinin Type B Receptor (CCKBR), N-His

Cat. No.AP9C452

Product TypeAnimal Proteins

Size

Product Overview

BioVenic's Recombinant Bovine Gastrin/Cholecystokinin Type B Receptor (CCKBR), N-His is a recombinant protein expressed from E.coli. Its predicted molecular weight is N/A. The purity is>97% (SDS-PAGE).

Specifications

Type Recombinant Protein
Species Bovine
Expression System E.coli
Purity >97% (SDS-PAGE)
Endotoxin < 1 EU/µg
Predicted Molecular Weight N/A
Physical State Lyophilized
Formulation The buffer before lyophilization is PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

Target Information

Bovine gastrin/cholecystokinin type B receptor (CCKBR) is a protein encoded by the CCKBR gene in humans. It is a multipass transmembrane receptor protein expressed in the central nervous system and gastrointestinal tract. This receptor is responsible for modulating anxiety, analgesia, arousal, and neuroleptic activity in the CNS, and it stimulates gastric acid secretion and mucosal growth in the GI tract. It mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. In Bovine, CCKBR plays a similar role, contributing to the regulation of digestion and potentially influencing other physiological processes such as anxiety and pain sensation, although specific Bovine functions may differ slightly from those in humans.

Protein Bovine Gastrin/Cholecystokinin Type B Receptor (CCKBR)
Protein Synonym CCK-A; CCK1; CCKRA; CCK1R; Cholecystokinin Type 1 Receptor
Gene ID 281665
UniProt ID P79266

Shipping and Storage

This product is shipped with dry ice. It is recommended to aliquot as needed and store at -80°C upon receipt. Reconstituted protein solution can be stored at 4°C for 1 week, at < -80°C for 12 months. Avoid repeated freezing and thawing.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

User Note

  1. Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Aliquot the reconstituted solution to minimise freeze-thaw cycles.
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